Group 9 – BioPRISM

The development of an affordable, efficient autosampler addresses the growing demand for automated laboratory workflows in university settings, where cost constraints often limit access to commercial solutions. Traditional autosamplers, priced between $10,000 and $50,000, are prohibitively expensive, motivating the creation of a device under $5,000 that meets the precision, reliability, and usability needs of academic laboratories. BioPRISM integrates advanced motion control, fluid management, thermal regulation, and an intuitive graphical interface, ensuring a versatile and user-friendly solution for sample collection, preparation, and delivery. Key innovations include a CORE XY gantry system for precise sample mobility, a syringe pump-based fluid extraction system to ensure accuracy and prevent cross-contamination, a modular thermal system for maintaining sample temperature, and a microcontroller-powered software interface for streamlined operations. Designed to support various tray formats—including two 96-well plates, 1.5 mL vials, and 15 mL vials—the system efficiently handles multiple sample types. The device improves university laboratory efficiency by automating complex workflows while maintaining high standards of accuracy and reproducibility. By leveraging cost-effective technologies inspired by 3D printers and CNC machines, the design delivers a scalable, high-performance autosampler, offering universities a practical alternative to commercial models and enhancing laboratory capabilities across research and education.