Group 10 – SampleSmart

The objective of our semester was to conceptualize, generate, and analyze the design of a fully functional fluid autosampler. This process included but was not limited to designing for cost effectiveness, open-source compatibility, and overall functionality. Due to the fact that commercial autosamplers often cost between $10,000 and $50,000, our design focuses on the scalability and user experience of the manufacturing and assembly process while also managing budgets and meeting time deadlines. Our solution features a simple, box-like structure that integrates stepper motors for the precise control of the sampling process, along with a fluid management system that uses a solenoid valve. The device comprises two primary sub-modules: a storage compartment that maintains multiple samples at a controlled temperature to ensure sample integrity, and a sampling and distribution apparatus for the efficient collection, delivery, and preparation of samples for downstream analysis. We also incorporated a temperature control system and tray adaptation mechanism to make our design efficient while minimizing costs. This simple yet robust design not only meets the customer’s requirement for scalability and performance but also significantly assists with budget management, making it accessible for not only laboratory areas but also smaller venues. By adopting technologies similar to those used in CNC machines and 3D printers, we ensured that our autosampler provides high accuracy while remaining user-friendly and feasible for diverse laboratory settings. Our biofluid autosampler successfully addresses the need for an effective yet affordable solution for biological sample analysis. The use of simple yet effective components, such as stepper motors, a solenoid valve, and a straightforward temperature control system utilizing convection control, allows for reliable sample handling while maintaining the integrity of the samples.